One man certain to start is Nicky Bailey who scored both of the Addicks goals in the 2-2 draw.
Phil Parkinson is set to name the same back four in front of keeper Rob Elliot, with Jay McEveley coming through Friday's match unscathed after his return from a shoulder injury.
Keith Gillespie has returned to the Blades after his loan spell so Lloyd Sam and Hameur Bouazza will start on the wings.
After no wins in his seven games in charge, today's match is Parkinson's last before the position is reviewed and with former Blackburn boss Paul Ince reportedly being interviewed on Monday, then a win is a must if he wants to stay in South London.
Possible side for Sheffield United: Elliot, Cranie, Fortune, Hudson(C), McEveley, Sam, Semedo, Bailey, Bouazza, Burton, Gray
Subs: Weaver, Holland, Waghorn, Shelvey, Basey